[AllUsers-ISR] Palestra: Neurorobotics model of Parkinson's Disease | 07/02 (14h30) no Anfiteatro do ISR

[Urbano J. Nunes]

Boa tarde,

Informamos que vai decorrer na próxima 2a feira uma palestra, sobre o 
tema "*Neurorobotics model of Parkinson's Disease*" (detalhes abaixo 
incluídos), para a qual estão todos convidados.

Com os melhores cumprimentos
-- Urbano J. Nunes e Gabriel Pires
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*Local: *Anfiteatro do ISR
*Data/Hora:* 07/02/2022, com início às 14h30

*Título da Palestra: Neurorobotics model of Parkinson's Disease
Orador: ***Assistant Professor Dr. Renan C. Moioli (Digital Metropolis 
Institute (IMD) from the Federal University of Rio Grande do Norte, Brazil)
**
In this talk, I will first describe our work on developing a 
neurorobotics model of Parkinson's Disease (PD). PD is a 
neurodegenerative disorder, linked to the death of dopaminergic neurons 
at the substantia nigra pars compacta, which affects the normal dynamics 
of the basal ganglia-thalamus-cortex (BG-T-C) neuronal circuit of the 
brain. Although there are multiple mechanisms underlying the disease, a 
complete description of those mechanisms and molecular pathogenesis are 
still missing, and there is still no cure. In our computational model, 
we performed a data-driven approach in which a set of biologically 
constrained parameters is optimised using  evolutionary computation. 
Evolved models successfully resembled spectral signatures of local field 
potentials and single-neuron mean firing rates from healthy and 
parkinsonian marmoset monkey brain data. Eventually, we hope that our 
work may facilitate the investigation of the mechanisms of PD and 
support the development of new therapies. Then, in the final part of the 
talk, I'll highlight how spiking neural networks with biophysically 
plausible neural architectures, such as the one developed in our 
project, are being used in diverse applications. These networks are 
often faster and require less energy to operate, and may benefit from 
novel neuromorphic implementations.

Short Bio
Dr. Renan C. Moioli is an assistant professor at the Digital Metropolis 
Institute (IMD) from the Federal University of Rio Grande do Norte, 
Brazil, where he is also part of the Graduate Program in Bioinformatics. 
He has a D. Phil. in Cognitive Science from the University of Sussex 
(2013), UK, working at the Centre for Computational Neuroscience and 
Robotics (CCNR). From 2013 to 2018 he was a research fellow at the 
Edmond and Lily Safra International Institute of Neuroscience, Brazil. 
His research interests are in the fields of computational intelligence 
and intelligent robotics. He is currently a UK Royal Society Newton 
Advanced Fellow, working in close collaboration with Dr. Patricia Vargas 
and Heriot-Watt's Robotics Laboratory in the project "Neuro4PD: 
neurorobotics model of Parkinson's Disease".
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